Flowability is a critical parameter that affects the manufacturing process. It is defined as the ease with which a powder or granular material flows, and it is closely related to the particle size, shape, and distribution of the components in the mixture.
Magnesium stearate is commonly used for its lubricating and anti-adherent properties. It finds also application as a glidant; this means that just a small amount of it improves the flowability of the powders to be compressed. Measurements performed with the NETZSCH Kinexus rotational rheometer highlight the glidant function of magnesium stearate. The addition of 1% by weight of magnesium stearate in lactose powder, the most common filler in tableting processes, greatly improves flowability of lactose. This shows how sensitive and precise the NETZSCH Kinexus rotational rheometer is, also for the determination of the cohesion energy density of a powder.
Find out more in this article written by Dr. Ligia de Souza and Claire Strasser, Application Scientists at NETZSCH Analyzing & Testing:
By optimizing the flow properties of the powder mixture using the NETZSCH Kinexus rotational rheometer, pharmaceutical manufacturers can improve the consistency and quality of their products.