Engineering Adaptable Blood-Mimicking Fluids for Microvascular Applications

Blood exhibits complex mechanical behavior that changes with flow conditions and confinement. Reproducing these characteristics in laboratory models is therefore an important challenge for studying microvascular flow and developing reliable in vitro systems.

This webinar presents the development of adaptable multiphase blood-mimicking fluids designed to reproduce key aspects of blood flow under confined microvascular conditions. By combining hydrogel-based artificial erythrocytes with tunable plasma-phase analogues, the system enables the effective mechanical properties of the fluid to be adjusted to represent different deformation regimes.

Under confined flow, the artificial cells exhibit deformation behavior similar to that of human erythrocytes, demonstrating their potential as physiologically relevant model systems. The presentation will also highlight future applications, including the calibration and validation of lab-on-a-chip devices and other in vitro platforms for microcirculatory research.

Join us to learn how adaptable blood-mimicking fluids can help create more realistic experimental models for studying microvascular flow.

Our special guest:
M. Sc. Gesine Hentschel
Institute of Multiphase Processes of Leibniz University Hannover