
Thermal Analysis and Rheology for Pharmaceutical Applications
Thermal Analysis provides powerful analytical methods for research, development and quality control of active pharmaceutical ingredients (APIs), excipients and formulations.
This implies the determination of their physicochemical properties such as melting point, glass transition temperature and heat of fusion, compatibility studies to find suitable API-excipient combinations, purity assessments (eutectic purity) and characterization of polymorphic forms.
Kriechen (Rheologie)Creep is one of the earliest “controlled stress” rheometer tests that quite literally “creeps” the material, i.e. we measure over a relatively prolonged period the small movement (the creep defined as creep compliance, J) of the sample by applying a small constant stress.Rheology perfectly complements the analytical equipment of your laboratory and allows for the specification of a suitable viscosity for different pharmaceutical products, assessment of flow limits of ointments and creams, predictions of storage stability by means of oscillation measurements as well as the determination of mechanical characteristics of soft gels.
The following blog article will give you an idea about testing possibilities
- Reliable Characterization of Pharmaceuticals Using Thermal Analysis
- 5 reasons why to use DSC and TGA for testing pharmaceuticals
- How can rheology help in the development of a treatment for COVID-19
- The Importance of Purity Determination of Pharmaceuticals
- Monitoring the Polymorphism of Paracetamol by Means of DSC
- Drug excipient compatibility check during the development
- Rheology of Topical Treatments
- Rheology: De-stressing the test of time