Differential scanning calorimetry

DSC 300 Caliris® Select 

A versatile DSC, tailor-made for your application!


The DSC 300 Caliris® Select is a Comprehensive, Reliable and Versatile DSC for Material Characterization and Tailor-Made for Your Applications. 

No matter if you are working in research & development, quality control, contract testing or the specification of materials for certain applications, information about a material's behavior under changing temperature and different atmospheres is important.

The DSC 300 Caliris® can support:

  • Material identification
  • Process optimization
  • Quality control
  • Phase diagrams
  • Kinetic analysis
  • Compatibility

The DSC 300 Caliris® Select – Tailor Made for Your Application

In the Select version of the DSC 300 Caliris®, there is an initial choice between three currently available modules. The maximum temperature range available in the DSC 300 Caliris® Select is -170°C to 650°C. The Select version allows for the exchange of modules of the same type avoiding instrument downtimes. 

It comes with integrated color touch display, an LED status bar and can optionally be equipped with an automatic sample changer.

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Modular Design – Maximum Flexibility

Ever-accelerating new material developments, triggered by fast-moving mobility and technical trends, require continuous adaptability. The new generation of NETZSCH DSCs is based on a modular concept. The DSC 300 Caliris® Series is the only instrument series of its kind with interchangeable and exchangeable sensor-furnace modules.  


The Standard Module
 -170°C to 600°C 

The routine module combines high stability and optimized resolution of thermal effects. Laser-guided welding processes for the sensor disks and thermocouple wires yield true sensitivity and robustness. The monolithic DSC sensor features high metrological stability and optimal resolution. The easy to handle S-module is the module of choice for industry and contract laboratories when routine measurements are the main task.


The Polymer-Module
-170°C to 600°C 

This module is perfect for all tasks in the polymer field. Its optimized low-mass furnace allows for heating rates of up to 500 K/min over a wide measurement range. Temperature profiles approximating real processing conditions can be realized. Additionally, one can speed up the measurements and thus save valuable time. The P-Module is perfect for research and development or quality control in the polymer processing industry.


High-Performance Module 
-180°C to 750°C

The premium module impresses with a perfect baseline and outstanding reproducibility. The very small peak-to-peak noise ratio allows the detection even of the smallest peaks – the gold standard for most DSC applications. In combination with the Supreme version, this module covers the entire temperature range from -180°C to 750°C. The H-Module is an ideal complement for advanced materials research and development in both industry and academia.

The German Design Award is presented annually by the German Design Council, Germany's trademark and design authority, on behalf of the highest authority for new developments in the German design industry. 

The DSC 300 Caliris®Supreme & Select receives the "Gold" Award in January 2024. This is the highest honor awarded for excellent, holistic and innovative design achievements!

Read the blog article


Differential Scanning Calorimetry (DSC) / Differential Thermal Analysis (DTA) 

Differential scanning calorimetry (DSC) is most frequently used thermoanalytical method to determine EndothermicA sample transition or a reaction is endothermic if heat is needed for the conversion.endothermic and ExothermicA sample transition or a reaction is exothermic if heat is generated.exothermic transitions like the determination of transformation temperatures and enthalpy of solids and liquids. It measures the difference between the heat flow rate into a sample versus into a reference as a function of temperature/time.

DSC is widely used in various fields such as polymer science, pharmaceuticals, food and cosmetics, organics and inorganics. It provides critical information about material properties like melting points, CrystallizationCrystallization is the physical process of hardening during the formation and growth of crystals. During this process, heat of crystallization is released.crystallization temperatures, Phase TransitionsThe term phase transition (or phase change) is most commonly used to describe transitions between the solid, liquid and gaseous states.phase transitions and purity.

Measuring Principle of Differential Scanning Calorimetry 

The measurement principle of Differential Scanning Calorimetry (DSC) is based on monitoring the difference in the amount of heat required to raise the temperature of a sample and a reference material at the same rate. Because the sample and reference are exposed to identical temperature conditions, any difference in heat flow between them is measured. This difference indicates that the sample is undergoing physical or chemical changes such as melting, CrystallizationCrystallization is the physical process of hardening during the formation and growth of crystals. During this process, heat of crystallization is released.crystallization, or chemical reactions that either absorb or release heat. 

A DSC measuring cell consists of a furnace and an integrated heat-flux sensor with designated positions for the sample and reference pans.

The DSC instrument records these heat flow differences as the temperature changes, providing a detailed profile of the sample's thermal properties and transitions.

The DSC systems are based on relevant instrument and application standards, e.g., ISO 11357, ASTM E793, ASTM D3895, ASTM D3417, ASTM D3418, DIN 51004, DIN 51007.


Technical Data

Maximum Temperature Range
-180°C to 750°C 
Maximum Heating Rate
0.001 K/min to 500 K/min
Automatic Sample Changer 
192+12 positions

Enthalpy precision (H-Module):
± 0.05% for indium

Temperature precision (H- and P-Module): 
± 0.01 K (standard deviation from mean value, indium)

Temperature accuracy (H-Module): 
± 0.05 K (Indium)

Peak-to-peak noise ratio:
± 2 µW

± 0.3% (peak area; In, C10H16, Zn)

Gas atmospheres:
Inert, oxidizing, static and dynamic

Cooling options:

  • Compressed air cooling (RT to 650°C/750°C)
  • Vortex tube (compressed air): < 0°C to 650°C/750°C
  • Compressed air with switch valve RT to 650°C/750°C
  • IC40 (-40°C to 600°C)
  • IC70 (-70°C to 600°C)
  • IC90 (-90°C to 600°C)
  • LN2 (-180°C to 650°C/750°C)

Heating/cooling rate:

  • H-Module: 0.001 K/min to 200 K/min
  • P-Module: 0.001 K/min to 500 K/min
    (Maximum rates depend upon end temperature)
  • S-Module: 0.001 K/min to 100 K/min
Sensor Guide Light
Example: DSC 300 Caliris® Supreme + UV-Accessory

Investigate Curing Reactions with Photo-Calorimeter.

For investigating Curing (Crosslinking Reactions)Literally translated, the term “crosslinking“ means “cross networking”. In the chemical context, it is used for reactions in which molecules are linked together by introducing covalent bonds and forming three-dimensional networks.curing reactions initiated by irradiation, such as UV or light, the ideal instrument to use is a photo-calorimeter or UV-DSC. The DSC 300 Caliris®, equipped with a UV accessory, is specifically designed for this purpose. In this instrument, the light guides are permanently installed in the moving furnace lid, ensuring immediate readiness for UV measurements. When needed, it is simple to exchange the lid to switch back to conventional DSC measurements, thus covering the entire temperature range.

Recommended light sources:

  • OmniCure®® S 2000: wavelength range 320 nm to 500 nm
  • LX500: wavelengths of 365 nm, 385 nm, 395 nm and 405 nm.
  • However, if desired, other commercial lamps can also be adapted for use.


Control your measurements without logging into the PC 


Proteus® Software – The Easy Approach to Your Work

Proteus®: Excellent Thermal Analysis Software

The DSC 300 Caliris® runs under Proteus® software on Windows and includes everything you need to carry out a measurement and evaluate the generated data. The combination of intuitive menus and automated routines makes data interpretation straightforward, even on advanced tasks. The Proteus® software is licensed with the instrument but can also be installed on other computer systems.

This instrument is LabV®️-primed

LabV®️ takes the data from your analytical instrument: It automatically imports all measurement data into a central and secure database solution, the LabV®️ software. This allows you to visualize the data in LabV®️ and to make them searchable. Your data will now be accessible from anywhere. Moreover you have the possibility to generate reports.

Consultancy & Sales

Do you have further questions about the instrument, the method and would you like to speak to a sales representative?

Service & Support

Do you already have an instrument and need technical support or spare parts?

Related Devices

  • DSC 300 Caliris® Classic

    Quality assurance of polymers, food, cosmetics and organics

    • Compact design for more space in the lab
    • Temperature range: -170°C to 600°C
    • Automatic Sample Changer: Up to 20 samples and references
  • DSC 300 Caliris® Supreme

    Quality assurance of polymers, food, cosmetics and organics

    • Three easily interchangeable modules: Standard, Polymer and High-Performance
    • Temperature range: -180°C to 750°C
    • UV-Accessory: Investigate Curing Reactions with Photo-Calorimeter
  • DSC 204 HP Phoenix®

    The high-pressure Differential Scanning Calorimeter for specific reactions

    • Pressure range from vacuum to 15 MPa (150 bar)
    • Temperature range: -150°C to 600°C
    • Measurements in inert, reducing and oxidizing atmospheres

KEYNOTE – Caliris® Supreme & Select

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Application Literature